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Blog posts : "skylar marvel"

Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways (2019) Computational Toxicology

Joint retreat in Oregon with Tanguay + Reif labs

The Tanguay + Reif labs met in Oregon for their second joint retreat. 

The retreat started with scientific sessions and lab tours at Oregon State University and the Sinnhuber Aquatic Research Lab (SARL) in Corvallis. We then moved to the Oregon Coast for more scientific sessions, hiking, and int…

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ToxPi software updated (v2.2) @ www.toxpi.org

The complete .zip is available for free download at: www.toxpi.org

This update adds flexibility for setting weights, offers improved "zoom" capabilities, updates information included in the saved Results Table object, and fixes issues identified by users.

The updated manual includes a full …

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Updated ToxPi version (v 2.1) available at www.toxpi.org

A major update to the ToxPi interface (version 2.1) is now available at:

www.toxpi.org

This update includes major speed improvements (especially noticeable when clustering large datasets), the ability to zoom/pan on cluster dendrograms, as well as other refinements for GUI users. 

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Updated ToxPi version (20180329) available at www.toxpi.org

http://toxpi.org/

ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models (2018) BMC Bioinformatics

Marvel SW, To K, Grimm FA, Wright FA, Rusyn I, Reif DM. ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models. BMC Bioinformatics. 2018 Mar 5;19(1):80. doi: 10.1186/s12859-018-2089-2. PubMed PMID: 29506467.

 

https://bmcbioinformatics.bi…

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Flash Report: SEAZIT Ontologies Workshop

A report on the SEAZIT (Systematic Evaluation of the Application of Zebrafish in Toxicology) Ontologies Workshop has been published:

https://ntp.niehs.nih.gov/iccvam/methods/dev-repro/ontologies-wksp-rept-2017.pdf

Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo [a] pyrene in zebrafish (2017) Toxicology and Applied Pharmacology

Knecht AL, Truong L, Marvel SW, Reif DM, Garcia A, Lu C, Simonich MT,
Teeguarden JG, Tanguay RL. Transgenerational inheritance of neurobehavioral and
physiological deficits from developmental exposure to benzo[a]pyrene in
zebrafish. Toxicol Appl Pharmacol. 2017 Jun 3;329:148-157. doi:
10.1016/…

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Aggregate entropy scoring for quantifying activity across endpoints with irregular correlation structure (2016) Reproductive Toxicology

Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM. Aggregate entropy scoring
for quantifying activity across endpoints with irregular correlation structure.
Reprod Toxicol. 2016 Apr 27;62:92-99. doi: 10.1016/j.reprotox.2016.04.012. [Epub 
ahead of print] PubMed PMID: 27132190.

Selected as cov…

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High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes (2015) Archives of Toxicology

High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes (2015) Archives of Toxicology

http://www.ncbi.nlm.nih.gov/pubmed/26126630

(NOTE: Full-text available for free via link above or here)

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Bioinformaticists at the bench

The Reif Lab packed up their laptops and journeyed to Robert Tanguay's lab for a scientific retreat at Oregon State University.

The retreat was packed with scientific presentations, discussion, and socializing. A highlight was seeing the amazing, custom-engineered setup of the laboratory. Li…

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Skylar Marvel joins the Reif Lab!

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12 blog posts