Gonzalez RD, Small GW, Green AJ, Akhtari FS, Havener TM, Quintanilha JCF, Cipriani AB, Reif DM, McLeod HL, Motsinger-Reif AA, Wiltshire T. RYK Gene Expression Associated with Drug Response Variation of Temozolomide and Clinical Outcomes in Glioma Patients. Pharmaceuticals. 2023; 16(5):726. https:…
Blog posts : "Publications"
Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst (2023) J Immunotoxicol
Phelps DW, Palekar AI, Conley HE, Ferrero G, Driggers JH, Linder KE, Kullman SW, Reif DM, Sheats MK, DeWitt JC, Yoder JA. Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst. J Immunotoxicol. 2023 Dec;20(1):2176953. doi: 10.1080/1547691X.2023.2176953. PM…
Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure (2022) Toxics
Thunga P, Truong L, Rericha Y, Du J, Morshead M, Tanguay RL, Reif DM. Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure. Toxics. 2022 Dec 9;10(12):769. doi: 10.3390/toxics10120769. PMID: 36548602; PMCID: PMC9781692.
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Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke (2022) Environ Int.
Carberry CK, Koval LE, Payton A, Hartwell H, Ho Kim Y, Smith GJ, Reif DM, Jaspers I, Ian Gilmour M, Rager JE. Wildfires and extracellular vesicles: Exosomal MicroRNAs as mediators of cross-tissue cardiopulmonary responses to biomass smoke. Environ Int. 2022 Jul 16;167:107419. doi: 10.1016/j.envint.2…
Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research (2022) Front. Tox
Kyle Roell, Lauren E. Koval, Rebecca Boyles, Grace Patlewicz, Caroline Ring, Cynthia V. Rider, Cavin Ward-Caviness, David M. Reif, Ilona Jaspers, Rebecca C. Fry and Julia E. Rager. Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological …
Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response (2022) Public Health Reports
Wolkin A, Collier S, House J, Reif D, Motsinger-Reif A, Duca L, Sharpe D. Comparison of National Vulnerability Indices Used by the Centers for Disease Control and Prevention for the COVID-19 Response. Public Health Rep. 2022 May 5:333549221090262. doi: 10.1177/00333549221090262. Epub ahead of print.…
Principles of Toxicology: Environmental and Industrial Applications, 4th Edition
Principles of Toxicology: Environmental and Industrial Applications, 4th Edition. Stephen M. Roberts (Editor), Robert C. James (Editor), Phillip L. Williams (Editor). ISBN: 978-1-119-63516-1.
David Reif co-authored Chapter 6 "Computational Toxicology", with Richard S. Judson, David M. Reif, Keit…
Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model (2022) Frontiers in Toxicology
Dylan James Wallis, Jane La Du, Preethi Thunga, Daniel Elson, Lisa Truong, Siva Kumar Kolluri, Robyn Leigh Tanguay, David M Reif. Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model. 29 April 2022. Fro…
ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS (2022) J Expo Sci Environ Epidemiol.
Fleming J, Marvel SW, Supak S, Motsinger-Reif AA, Reif DM. ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS. J Expo Sci Environ Epidemiol. 2022 Apr 26. doi: 10.1038/s41370-022-00433-w. Epub ahead of print. PMID: 35474345.
Convergent evolution of polyploid genomes from across the eukaryotic tree of life (2022) G3
Hao Y, Fleming J, Petterson J, Lyons E, Edger PP, Pires JC, Thorne JL, Conant GC. Convergent evolution of polyploid genomes from across the eukaryotic tree of life. G3 (Bethesda). 2022 Apr 22:jkac094. doi: 10.1093/g3journal/jkac094. Epub ahead of print. PMID: 35451464.
The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior (2022) Toxicological Sciences
Shankar P, Garcia GR, LaDu JK, Sullivan CM, Dunham CL, Goodale BC, Waters KM, Stanisheuski S, Maier CS, Thunga P, Reif DM, Tanguay RL. The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior. Toxicol Sci. 2022 Apr 4:kfac037. doi: 10.1093/toxsci/kfac037. Epub ahead …
Kirkwood et al. pub recognized as "NIEHS Paper of the Month"
https://factor.niehs.nih.gov/2022/4/papers/dert/index.htm
Pine needles work as passive samplers for PFAS
NIEHS-funded researchers showed that pine needles can be used as a tool to monitor the presence and distribution of per- and polyfluoroalkyl substances (PFAS) over time. The pine needle’s w…
Implementation of Zebrafish Ontologies for Toxicology Screening (2022) Frontiers in Toxicology
Anne E Thessen, Skylar Marvel, J. C. Achenbach, Stephan Fischer, Melissa Anne Haendel, Kimberly Hayward, Nils Klüver, Sarah Könemann, Jessica Legradi, Pamela J Lein, Connor Leong, Arantza Muriana, J. Erik Mylroie, Stephanie Padilla, Dante Perone, Antonio Planchart, Rafael Miñana Prieto, Celia Queved…
Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish (2022) J Hazard Mater
Truong L, Rericha Y, Thunga P, Marvel S, Wallis D, Simonich MT, Field JA, Cao D, Reif DM, Tanguay RL. Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish. J Hazard Mater. 2022 Mar 2;431:128615. doi: 10.1016/j.jhazmat.2022.128615. Epub ahead of print. P…
Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (2022) Environ Sci Technol.
Kirkwood KI, Fleming J, Nguyen H, Reif DM, Baker ES, Belcher SM. Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS). Environ Sci Technol. 2022 Feb 17. doi: 10.1021/acs.est.1c06483. Epub ahead of print. PMID: 35175744.
https://pubmed.ncbi.nlm.nih.…
Collaborative paper featuring Jonathon's work highlighted in the news
https://news.ncsu.edu/2022/02/pine-needles-story-of-nc-pfas/
Pine Needles Tell the Story of PFAS in North Carolina
Demonstrating a systems approach for integrating disparate data streams to inform decisions on children's environmental health (2022) BMC Public Health
Hubal EAC, DeLuca NM, Mullikin A, Slover R, Little JC, Reif DM. Demonstrating a systems approach for integrating disparate data streams to inform decisions on children's environmental health. BMC Public Health. 2022 Feb 15;22(1):313. doi: 10.1186/s12889-022-12682-3. PMID: 35168583; PMCID: PMC8845296…
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs (2021) PLoS Genetics
Akhtari FS, Green AJ, Small GW, Havener TM, House JS, Roell KR, Reif DM, McLeod HL, Wiltshire T, Motsinger-Reif AA. High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticance…
Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology (2021) PLoS Comput Biol
Green AJ, Mohlenkamp MJ, Das J, Chaudhari M, Truong L, Tanguay RL, et al. (2021) Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology. PLoS Comput Biol 17(7): e1009135. https://doi.org/10.1371/journal.pcbi.1…
Concurrent evaluation of mortality and behavioral responses: A fast and efficient testing approach for high-throughput chemical hazard identification (2021) Frontiers in Toxicology
Thunga P, Truong L, Tanguay RL, Reif DM. Concurrent evaluation of mortality and behavioral responses: A fast and efficient testing approach for high-throughput chemical hazard identification. Frontiers in Toxicology. 2021.
10.3389/ftox.2021.670496
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