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Blog posts

Reif presents at OpenTox conference

David Reif presented at the 2017 OpenTox USA meeting. Thanks to Barry Hardy and Noffisat Oki for the invitation to speak! 

His seminar was entitled "Implications of Population Genetic Diversity for Safety Assessment."  

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Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo [a] pyrene in zebrafish (2017) Toxicology and Applied Pharmacology

Knecht AL, Truong L, Marvel SW, Reif DM, Garcia A, Lu C, Simonich MT,
Teeguarden JG, Tanguay RL. Transgenerational inheritance of neurobehavioral and
physiological deficits from developmental exposure to benzo[a]pyrene in
zebrafish. Toxicol Appl Pharmacol. 2017 Jun 3;329:148-157. doi:
10.1016/…

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Reif presents at International Neurotoxicology Association meeting in Brazil

David Reif presented at the joint meeting of the International Neurotoxicology Association & Neurotoxicity Society in Florianopolis, Brazil. 

The seminar was entitled "Developing an Integrated Testing Strategy: Analytical methods to distill useful information from high-throughput screening of ch…

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Reif, Kosnik, and Hoppin present at the University of Wollongong, Australia

David Reif, Marissa Kosnik, and Jane Hoppin traveled to Australia to present and collaborate with researchers at the University of Wollongong. The trip was sponsored by a grant from the University Global Partnership Network (UGPN). Our hosts were Thomas Astell-Burt and Xiaoqi Feng, who direct the Po…

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An introduction to terminology and methodology of chemical synergy -perspectives from across disciplines (2017) Frontiers in Pharmacology

Reif presents at ToxForum annual meeting

David Reif presented an invited talk at the 41st Annual ToxForum Winter Meeting in Washington, DC.

The talk, "Integrating Multiple Sources of High-Dimensional Data to Quantify Effects of Genetic Variability in Chemical Risk Assessment", was part of a session moderated by Julia Rager & Reza Rasoulpo…

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Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish

Zhang G., Truong L., Tanguay R.L., Reif D.M. (2017) Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish. In: Kalueff A. (eds) The rights and wrongs of zebrafish: Behavioral phenotyping of zebrafish. Springer, Cham.

http://www.springer.com/us/book/9783319337739

https://l…

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Incorporating ToxCast and Tox21 datasets to rank biological activity of chemicals at Superfund sites in North Carolina (2017) Environment International

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Reif presents in Systematic Evaluation of the Application of Zebrafish in Toxicology (SEAZIT) series

David Reif presented as part of the ongoing Systematic Evaluation of the Application of Zebrafish in Toxicology (SEAZIT) webinar series. 

The Proximity Principle

Christy Sadler and colleagues have written a new multimedia article about the Bioinformatics "cluster" at NC State University.

https://sciences.ncsu.edu/news/the-proximity-principle

The term "cluster" is shorthand for the cluster hiring program known as the Chancellor's Faculty Excellence Prog…

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A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish (2017) PLoS One

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Evolutionary and Functional Diversification of the Vitamin D Receptor-Lithocholic Acid Partnership (2016) PLoS One

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A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades (2016) TAAP

Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM. A data-driven weighting
scheme for multivariate phenotypic endpoints recapitulates zebrafish
developmental cascades. Toxicol Appl Pharmacol. 2016 Nov 21. pii:
S0041-008X(16)30365-9. doi: 10.1016/j.taap.2016.11.010. [Epub ahead of print]
PubMed …

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Embryonic exposure to TCDD impacts osteogenesis of the axial skeleton in Japanese medaka, Oryzias latipes (2016) Toxicological Sciences

Embryonic exposure to TCDD impacts osteogenesis of the axial skeleton in Japanese medaka, Oryzias latipes. ALTD Watson, A Planchart, CJ Mattingly, C Winkler, DM Reif, SW Kullman. Toxicological Sciences, kfw229

http://toxsci.oxfordjournals.org/content/early/2016/11/14/toxsci.kfw229.full.pdf+html

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Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes (2016) Metabolomics

Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes. CHS Chialvo, R Che, D Reif, A Motsinger-Reif, LK Reed. Metabolomics 12 (11), 167.

http://link.springer.com/article/10.1007/s11306-016-1117-3

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Reif presents at Triangle Statistical Genetics Meeting

David Reif presented an invited talk at the 2016 Triangle Statistical Genetics Meeting. The event was hosted at SAS, Inc. by the Triangle StatGen Organizing Committee.

 

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Article featured as Editor's Highlight in Toxicological Sciences

Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S,
Wambaugh J, Woodrow Setzer R, Kothya P, Phuong J, Filer D, Smith D, Reif D,
Rotroff D, Kleinstreuer N, Sipes N, Xia M, Huang R, Crofton K, Thomas RS.
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicit…

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Marissa Kosnik joins the Reif Lab!

Bio

Marissa is pursuing her PhD in the Toxicology graduate program.

Guozhu Zhang successfully defends his PhD dissertation!

Guozhu Zhang successfully defended his doctoral (PhD) dissertation at the BRC

His dissertation is entitled "Analytical Tools for Characterizing Developmental Toxicity of Environmental Chemicals Using High-Throughput Screening in Zebrafish". 

Guozhu's committee members were David Reif (Ch…

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Advancing toxicology research using in vivo high throughput toxicology with small fish models (2016) ALTEX

Planchart A, Mattingly CJ, Allen D, Ceger P, Casey W, Hinton D, Kanungo J,
Kullman SW, Tal T, Bondesson M, Burgess SM, Sullivan C, Kim C, Behl M, Padilla S,
Reif DM, Tanguay RL, Hamm J. Advancing toxicology research using in vivo high
throughput toxicology with small fish models. ALTEX. 2016 Ju…

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20 blog posts