Hao Y, Fleming J, Petterson J, Lyons E, Edger PP, Pires JC, Thorne JL, Conant GC. Convergent evolution of polyploid genomes from across the eukaryotic tree of life. G3 (Bethesda). 2022 Apr 22:jkac094. doi: 10.1093/g3journal/jkac094. Epub ahead of print. PMID: 35451464.
Blog posts : "Publications"
The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior (2022) Toxicological Sciences
Shankar P, Garcia GR, LaDu JK, Sullivan CM, Dunham CL, Goodale BC, Waters KM, Stanisheuski S, Maier CS, Thunga P, Reif DM, Tanguay RL. The Ahr2-Dependent wfikkn1 Gene Influences Zebrafish Transcriptome, Proteome, and Behavior. Toxicol Sci. 2022 Apr 4:kfac037. doi: 10.1093/toxsci/kfac037. Epub ahead …
Kirkwood et al. pub recognized as "NIEHS Paper of the Month"
https://factor.niehs.nih.gov/2022/4/papers/dert/index.htm
Pine needles work as passive samplers for PFAS
NIEHS-funded researchers showed that pine needles can be used as a tool to monitor the presence and distribution of per- and polyfluoroalkyl substances (PFAS) over time. The pine needle’s w…
Implementation of Zebrafish Ontologies for Toxicology Screening (2022) Frontiers in Toxicology
Anne E Thessen, Skylar Marvel, J. C. Achenbach, Stephan Fischer, Melissa Anne Haendel, Kimberly Hayward, Nils Klüver, Sarah Könemann, Jessica Legradi, Pamela J Lein, Connor Leong, Arantza Muriana, J. Erik Mylroie, Stephanie Padilla, Dante Perone, Antonio Planchart, Rafael Miñana Prieto, Celia Queved…
Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish (2022) J Hazard Mater
Truong L, Rericha Y, Thunga P, Marvel S, Wallis D, Simonich MT, Field JA, Cao D, Reif DM, Tanguay RL. Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish. J Hazard Mater. 2022 Mar 2;431:128615. doi: 10.1016/j.jhazmat.2022.128615. Epub ahead of print. P…
Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (2022) Environ Sci Technol.
Kirkwood KI, Fleming J, Nguyen H, Reif DM, Baker ES, Belcher SM. Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS). Environ Sci Technol. 2022 Feb 17. doi: 10.1021/acs.est.1c06483. Epub ahead of print. PMID: 35175744.
https://pubmed.ncbi.nlm.nih.…
Collaborative paper featuring Jonathon's work highlighted in the news
https://news.ncsu.edu/2022/02/pine-needles-story-of-nc-pfas/
Pine Needles Tell the Story of PFAS in North Carolina
Demonstrating a systems approach for integrating disparate data streams to inform decisions on children's environmental health (2022) BMC Public Health
Hubal EAC, DeLuca NM, Mullikin A, Slover R, Little JC, Reif DM. Demonstrating a systems approach for integrating disparate data streams to inform decisions on children's environmental health. BMC Public Health. 2022 Feb 15;22(1):313. doi: 10.1186/s12889-022-12682-3. PMID: 35168583; PMCID: PMC8845296…
High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs (2021) PLoS Genetics
Akhtari FS, Green AJ, Small GW, Havener TM, House JS, Roell KR, Reif DM, McLeod HL, Wiltshire T, Motsinger-Reif AA. High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticance…
Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology (2021) PLoS Comput Biol
Green AJ, Mohlenkamp MJ, Das J, Chaudhari M, Truong L, Tanguay RL, et al. (2021) Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology. PLoS Comput Biol 17(7): e1009135. https://doi.org/10.1371/journal.pcbi.1…
Concurrent evaluation of mortality and behavioral responses: A fast and efficient testing approach for high-throughput chemical hazard identification (2021) Frontiers in Toxicology
Thunga P, Truong L, Tanguay RL, Reif DM. Concurrent evaluation of mortality and behavioral responses: A fast and efficient testing approach for high-throughput chemical hazard identification. Frontiers in Toxicology. 2021.
10.3389/ftox.2021.670496
Extending the lymphoblastoid cell line model for drug combination pharmacogenomics (2021) Pharmacogenomics
Green AJ, Anchang B, Akhtari FS, Reif DM, Motsinger-Reif A. Extending the lymphoblastoid cell line model for drug combination pharmacogenomics. Pharmacogenomics. 2021 May 28. doi: 10.2217/pgs-2020-0160. Epub ahead of print. PMID: 34044623.
https://pubmed.ncbi.nlm.nih.gov/34044623/
Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments (2021) Analytical Chemistry
Odenkirk MT, Reif DM, Baker ES. Multiomic Big Data Analysis Challenges: Increasing Confidence in the Interpretation of Artificial Intelligence Assessments. Anal Chem. 2021 May 24. doi: 10.1021/acs.analchem.0c04850. Epub ahead of print. PMID: 34029068.
Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions (2021) Toxics
Wallis DJ, Truong L, La Du J, Tanguay RL, Reif DM. Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions. Toxics. 2021; 9(4):77. https://doi.org/10.3390/toxics9040077
Abstract
Exposure to endocrine-disrupting che…
Development of a Pandemic Awareness STEM Outreach Curriculum: Utilizing a Computational Thinking Taxonomy Framework (2021) Education Sciences
Gilchrist PO, Alexander AB, Green AJ, Sanders FE, Hooker AQ, Reif DM. Development of a Pandemic Awareness STEM Outreach Curriculum: Utilizing a Computational Thinking Taxonomy Framework. Education Sciences. 2021; 11(3):109. https://doi.org/10.3390/educsci11030109
Abstract
Computational thin…
Children's Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals (2020) Int J Environ Res Public Health
- PMCID: PMC7696947
Cohen Hubal EA, Reif DM, Slover R, Mullikin A, Little JC. Children's Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals. Int J Environ Res Public Health. 2020 Nov 11;17(22):8337. doi: 10.3390/ijerph172…
Graphic by Melanie Odenkirk makes the cover of the journal Analyst
https://pubs.rsc.org/en/content/articlelanding/2020/an/d0an90119a#!divAbstract
From the article:
Odenkirk MT , Zin PPK , Ash JR , R…
[COVER ARTICLE] Structural-based connectivity and omic phenotype evaluations (SCOPE): a cheminformatics toolbox for investigating lipidomic changes in complex systems (2020) Analyst
Structural-based connectivity and omic phenotype evaluations (SCOPE): a cheminformatics toolbox for investigating lipidomic changes in complex systems
The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity (2020) Reproductive Toxicology
The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity. Truong L, Marvel S, Reif DM, Thomas D, Pande P, Dasgupta S, Simonich MT, Waters KM, Tanguay RL.Reprod Toxicol. 2020 Aug 19:S0890-6238(20)30196-9. doi: 10.1016/j.reprotox.2020.08.007. Online ahead of print.PMID:…
The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning (2021) Environmental Health Perspectives
Marvel SW, House JS, Wheeler M, Song K, Zhou YH, Wright FA, Chiu WA, Rusyn I, Motsinger-Reif A, Reif DM. The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning. Environ Health Perspect. 2021 Jan…